Initial experience with nifekalant hydrochloride (MS-551), a novel class III antiarrhythmic agent, in patients with acute extensive infarction and severe ventricular dysfunction.

نویسندگان

  • K Takenaka
  • S Yasuda
  • S Miyazaki
  • T Kurita
  • Y Sutani
  • I Morii
  • S Daikoku
  • S Kamakura
  • H Nonogi
چکیده

Nifekalant hydrocholoride, a novel class III antiarrhythmic agent, was used as the treatment in 4 patients with extensive anterior infarction and severe ventricular dysfunction. The malignant ventricular tachyarrhythmia was effectively suppressed at a relatively low dose, without compromising the hemodynamics, indicating that this potent K+ channel blocker has therapeutic potential for acute myocardial infarction.

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عنوان ژورنال:
  • Japanese circulation journal

دوره 65 1  شماره 

صفحات  -

تاریخ انتشار 2001